A Green Approach: Eosin Y-Facilitated Visible-Light Preparation of a Functionalized 1,2,3- Triazole Compound
Singh Disha1, Srivastava Nidhi2
1Disha Singh, Scholar, Department of Chemistry, Pt. Prithi Nath College (PG), Kanpur (Uttar Pradesh), India.
2Dr. Nidhi Srivastava, Professor, Department of Chemistry, Pt. Prithi Nath College, (PG) Kanpur (Uttar Pradesh), India.
Manuscript received on 30 May 2026 | First Revised Manuscript received on 01 August 2026 | Second Revised Manuscript received on 18 September 2026 | Manuscript Accepted on 15 October 2026 | Manuscript published on 30 October 2026 | PP: 9-13 | Volume-6 Issue-2, October 2026 | Retrieval Number: 100.1/ijac.B203706021026 | DOI: 10.54105/ijac.B2037.06021026
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© The Authors. Published by Lattice Science Publication (LSP). This is an open-access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: A key goal of contemporary organic chemistry is developing environmentally acceptable, sustainable methods for synthesising nitrogen-containing heterocycles. Because of their broad biological activities and medicinal chemistry applications, 1,2,3-triazoles have garnered considerable attention among these heterocycles. In this study, we developed a visible-light-induced process to synthesise (4-hexyl-2H-1,2,3-triazole-2-yl) methanol using Eosin Y as an organic photocatalyst. The reaction is a threecomponent coupling of formaldehyde, sodium azide, and terminal alkynes that occurs under visible light at ambient temperature. Eosin Y (5 mol%) in an H2O/DMSO (1:1) solvent system under blue LED irradiation yields the required triazole derivatives in good yield when reaction parameters are optimised. Control studies validated the crucial roles of visible light and the photocatalyst in the reaction. Without a transition-metal catalyst, the transformation proceeds under mild conditions, demonstrating the protocol’s environmental friendliness. We propose a viable photoredox process that generates reactive intermediates and activates Eosin Y under visible light. This process offers a straightforward, effective, and environmentally friendly way to create functionalized 1,2,3-triazole derivatives.
Keywords: Eosin Y, Heterocyclic Compounds, Visible Light Photo-Redox Catalyst, Green Synthesis, and 1,2,3-Triazoles.
Scope of the Article: Organic Chemistry